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Overwintering of West Nile virus in a bird community with a communal crow roost. Reisen W. Overwintering of West Nile virus in the United States. Support Center Support Center. External link. Please review our privacy policy. Insertional control viruses were also capable of neuroinvasion and neurovirulence in vivo in CD-1 mice.
Vaccine viruses were safe at all doses tested and did not demonstrate mutations associated with a reversion to virulence when serially passaged in mice. Overall, this is a safe and effective attenuation strategy with broad potential application for vaccine development. Abstract West Nile virus WNV is an important agent of human encephalitis that has quickly become endemic across much of the United States since its identification in North America in Publication types Research Support, Non-U.
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